Childhood sexual abuse predicts poor outcome seven years after parasuicide, ♥ psychologia - inne (książki, ...

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Soc Psychiatry Psychiatr Epidemiol (2004) 39 : 916–920
DOI 10.1007/s00127-004-0839-0
ORIGINAL PAPER
Stig Söderberg · Gunnar Kullgren · Ellinor Salander Renberg
Childhood sexual abuse predicts poor outcome seven years
after parasuicide
Accepted: 11 June 2004
■
Abstract
Background
There is substantial empirical
research linking borderline personality disorder with
prolonged mental instability and recurrent suicidality.
At the same time, a growing body of observations links
borderline personality disorder to sexual abuse and
other forms of abuse and trauma in childhood. The aim
of this study was to investigate among patients admitted
for parasuicide the predictive value for outcome 7 years
after the parasuicide of a diagnosis of borderline per-
sonality disorder compared to the predictive value of a
history of childhood sexual abuse.
Methods
Semi-struc-
tured interviews were conducted at the time of the index
parasuicide, with follow-up interviews 7 years later. In
addition, information was collected from medical
records at the psychiatric clinic. A logistic regression
analysis was used to assess the specific influence of the
covariates borderline personality disorder, gender and
reported childhood sexual abuse on the outcome vari-
ables.
Results
Univariate regression analysis showed
higher odds ratios for borderline personality disorder,
female gender and childhood sexual abuse regarding
prolonged psychiatric contact and repeated parasui-
cides. A combined logistic regression model found sig-
nificantly higher odds ratios only for childhood sexual
abuse with regard to suicidal ideation, repeated parasui-
cidal acts and more extensive psychiatric support.
Con-
clusion
The findings support the growing body of evi-
dence linking the characteristic symptoms of borderline
personality disorder to childhood sexual abuse, and
identify sexual abuse rather than a diagnosis of border-
line personality disorder as a predictor for poor out-
come after a parasuicide. The findings are relevant to
our understanding and treatment of parasuicide pa-
tients, especially those who fulfil the present criteria for
borderline personality disorder.
■
Key words
borderline personality disorder – sexual
abuse – suicidal ideation – parasuicide – follow-up
Introduction
Borderline personality disorder (BPD), a diagnostic cat-
egory that we find primarily in women, has been a focus
of research because of repeated findings of a very high
prevalence of parasuicide (Bongar et al. 1990; Söderberg
2001). Follow-up studies after parasuicide often focus
on the risk for repeated parasuicide and completed sui-
cide (Suokas et al. 2001; Jenkins et al. 2002; Ostamo and
Lonnqvist 2001; Tejedor et al. 1999). The BPD group has
been found to have an increased overall risk for repeated
parasuicides. The risk for completed suicide is around
10 %, which is comparable to other clinical groups such
as schizophrenia and mood disorders (Paris 2002).
The concept of borderline personality disorder with
its core symptoms of disturbed affect, cognition, impul-
sivity and interpersonal relationships implies prolonged
problems in psychosocial functioning. In the last few
years, however, an increasing number of studies have
linked the symptoms of borderline personality disorder
to sexual or physical abuse and neglect in childhood
(Brodsky et al. 1997; Soloff et al. 2002; Zanarini et al.
2002; Söderberg et al. 2004). The odds ratio for suicide
attempts among adults reporting childhood sexual
abuse has been estimated at 1.3–25.6 times higher than
among non-abused adults (Santa Mina and Gallop
1998). Coll et al. (2001) found that female overdose pa-
tients were 15 times more likely to have experienced sex-
ual abuse than matched controls. These findings suggest
that our understanding and treatment of the symptoms
presently classified as borderline personality disorder
may need revision.
The aim of our follow-up study 7 years after an index
parasuicide was to investigate whether the presence of
S. Söderberg, MD · G. Kullgren, MD, PhD · E. Salander Renberg, PhD
Dept. of Clinical Sciences, Psychiatry
Umeå University
901 85 Umeå, Sweden
Tel.: + 46-703268639
Fax: + 46-90770599
E-Mail: stig.soderberg@vll.se
917
■
Statistical methods
childhood sexual abuse might be a better predictor than
a diagnosis of borderline personality disorder for vari-
ous outcome measures such as recurrent suicidal
ideation, fatal and non-fatal suicidal behaviour, impair-
ment of psychosocial functioning and a need for psy-
chiatric support in the years following the index para-
suicide.
In comparison of means Student’s
t
-test was applied. The chi-square
test was used to test differences between groups in categorical vari-
ables, except where expected values were below five, in which case
Fisher’s exact probability test was used. We used a logistic regression
model to assess the specific influence on outcome variables of the co-
variates borderline personality disorder, female gender and sexual
abuse in childhood in terms of crude and adjusted odds ratios. The
adjusted odds ratios were controlled for age. The significance level
was set at p < 0.05.
Subjects and methods
Results
Over a 10-month period in 1995 and 1996, semi-structured interviews
were conducted with consecutive parasuicide patients admitted to in-
patient care at a somatic or psychiatric ward at Umeå University Hos-
pital in Sweden, which is the only inpatient hospital in the region. To
define the cohort to be studied, we used the WHO/EURO multicentre
study definition of parasuicide rather than the alternative terms at-
tempted suicide or deliberate self-harm, which define a somewhat dif-
ferent group of behaviours. Parasuicide was, thus, defined as a self-de-
structive act with a non-fatal outcome, aimed at realizing changes in
the life situation (Platt et al. 1992). Methodology and findings have
been described in detail in a previous paper (Söderberg 2001).
Of the 78 identified patients, five (three men and two women)
were excluded due to acute psychosis and nine (two men and seven
women) chose not to participate. The remaining 64 patients (81 %)
were included in the study. At the interview after the index parasui-
cide, 63 persons (98 %) gave their consent to be contacted for a follow-
up interview after a few years. We also obtained the approval of the
Research Ethics Committee of Umeå University for a follow-up inter-
view.
At the initial interview, 35 persons (55 %) met the criteria for bor-
derline personality disorder (BPD) according to DSM-IV, while 29
(45 %) did not fulfil these criteria (NoBPD). Within the NoBPD group,
15 (52 %) met the criteria for some other personality disorder (Söder-
berg 2001). Personality disorders were diagnosed using a version of
the Structured Clinical Interview for Personality Disorders (Spitzer
et al. 1992), adapted for DSM-IV (Ottosson et al. 1998).
Experience of childhood sexual abuse was common in the BPD
group (Söderberg et al. 2004), with 17 (65 %) of the women in the BPD
group reporting sexual abuse as a child compared to two of the
women (13 %) in the NoBPD group. Life events such as childhood sex-
ual abuse were investigated using the EPSIS Life Event Scale (Euro-
pean Parasuicide Study Interview Schedule) (Kerkhof et al. 1989). The
procedures and results have been described in detail in a previous ar-
ticle (Söderberg et al. 2004).
The follow-up interviews were conducted (by S. S.) over a 5-
month period starting in autumn 2002, with a mean time lapse be-
tween the first and second interview of 7.5 years (90 months, range
79–96 months). The majority of interviews were conducted by tele-
phone. The interview focused on life experiences in the years follow-
ing the index parasuicide, covering social relations, work situation
and psychiatric problems. We also obtained the consent of the per-
sons involved to review their medical records at the psychiatric clinic.
As outcome variables from the interview, we chose reported re-
current suicidal thoughts and parasuicidal acts. As an indicator of
psychosocial functioning, we chose the reported ability to sustain
work and partner relationships. From the medical records, we chose
the outcome variables duration of outpatient treatment at the psychi-
atric clinic during the follow-up period and presence of current psy-
chiatric in- or outpatient treatment at the time of the interview. Since
there are no other in- or outpatient psychiatric clinics in the region,
the records should sufficiently cover the treatment received.
When comparing the results of the initial and follow-up inter-
views, those persons who did not participate in the follow-up inter-
view were excluded from the original BPD and NoBPD groups.
We w e r e a b le to trace 61 (95 %) of the persons who took
part in the original interviews. One woman in the
NoBPD group had died of natural causes. Five people
(8 %), one man and one woman in the BPD group and
two men and one woman in the NoBPD group, had died
by suicide. Only one of these, a man in the BPD group,
had reported a history of childhood sexual abuse. There
was no significant difference with regard to borderline
personality disorder diagnosis, gender or childhood
sexual abuse for completed suicide.
Of the remaining 55 people contacted, 51 gave their
consent to participate in the follow-up interview, thus
covering 29 (83 %) of those in the original BPD group
and 22 (76 %) in the original NoBPD group. The overall
gender distribution was 19 men and 32 women.
The mean age was 37 years (range 24–59) in the BPD
group compared to 42 years (range 24–61) in the NoBPD
group (ns). There was a significant gender difference in
that 22 of 29 (76 %) in the BPD group were women com-
pared to 10 of 22 (46 %) in the NoBPD group (
2
= 4.948,
p=0.026). In the BPD group, 14 (48 %) had reported
childhood sexual abuse compared to one (5 %) in the
NoBPD group (
χ
χ
2
= 11.523, p = 0.001). All of these were
women.
For psychosocial functioning, Table 1 shows the sig-
nificant differences between the groups at the follow-up
interview not found at the index parasuicide. Table 1 also
shows figures on psychiatric care, suicidal thoughts and
parasuicidal acts during the follow-up period.
The mean duration of continued psychiatric contact
after the index parasuicide was 58 months in the BPD
group and 26 months in the NoBPD group (t = 2.782,
p=0.008). In the BPD group, 69 % had committed at
least one new parasuicide during the follow-up period
compared to 36 % in the NoBPD group (
2
= 5.370,
p=0.020). Repeated parasuicidal acts (two or more)
were also significantly more common in the BPD group,
as seen in Table 1.
Suicidal thoughts were not significantly more com-
mon in the BPD group than in the NoBPD group. The
most common suicidal thoughts were poisoning, re-
ported by 75 % in the BPD group and 32 % in the NoBPD
group, and of cutting oneself, reported by 41 % and 14 %,
respectively. Poisoning was also the most common para-
suicidal method, with 65 % and 27 %, respectively, fol-
lowed by cutting, with 28 % and 14 %, respectively.
χ
918
Table 1 Psychosocial functioning at index parasui-
cide and at follow-up interview. Psychiatric problems
and psychiatric care during the follow-up period after
index parasuicide (p < 0.05)
BPD
NoBPD
n%
n%
χ
2
p
At index parasuicide:
Living with a partner with or without children
12
41
8
36
0.132
0.716
Attending work or school
12
41
10
46
0.085
0.771
At follow-up interview:
Living with a partner with or without children
10
35
14
64
4.268
0.039
Attending work or school
6
21
13
59
7.892
0.005
Outpatient treatment
≥
3 years after index parasuicide
18
62
5
23
7.820
0.005
Current psychiatric treatment
16
55
5
23
5.437
0.020
Suicidal thoughts in the past 3 months
11
38
4
18
2.350
0.125
Repeated parasuicides during follow-up period
14
48
4
18
4.961
0.026
n = 51 (BPD = 29, NoBPD = 22)
The majority of the BPD group were women. Four-
teen (64 %) of the women in this group had reported ex-
perience of sexual abuse as a child compared to one
(10 %) in the NoBPD group (Fisher’s p = 0.007). None of
the men reported childhood sexual abuse. Univariate lo-
gistic regression analyses to assess the specific influence
of the covariates borderline personality disorder, female
gender and childhood sexual abuse showed significance
in most of the outcome measures (crude rates).
The univariate analysis was followed by a logistic re-
gression analysis with all covariates entered in the same
model. Since there were significant age differences in the
dependent variables, we also controlled for age. The fi-
nal model revealed significant odds ratios only for the
covariate childhood sexual abuse with respect to pres-
ence of psychiatric care, suicidal thoughts and repeated
parasuicidal acts. The adjusted odds ratios for the out-
come measures regarding psychosocial situation were
not significant for any of the covariates. The results are
given in Table 2.
gender or borderline personality disorder was found to
be the main factor influencing the outcome measures.
We found a strong relationship between childhood
sexual abuse and continued suicidal ideation and re-
peated parasuicidal acts in the follow-up period, as well
as a more extensive presence of psychiatric support. The
findings suggest that what at first may seem to be a char-
acteristic of those with borderline personality disorder
is better explained as a characteristic of sexually abused
women.
Sexual abuse is regarded as a very serious adverse life
event with long-term psychological consequences
(Finkelhor and Browne 1985; Herman 1992; Silverman
et al. 1996), including symptoms of depression, anxiety
and low self-esteem as well as suicidal behaviour (Briere
and Runtz 1988; Malinosky-Rummel and Hansen 1993;
Romans et al. 1995). The sequelae of childhood abuse de-
pend on its severity and the presence of protective fac-
tors (Malinosky-Rummel and Hansen 1993; Browne and
Finkelhor 1986), and in clinical populations sexual
abuse is often linked to other forms of abuse and neglect
in childhood (Brodsky et al. 1997; Soloff et al. 2002; Za-
narini et al. 2002; Söderberg et al. 2004).
Psychopathology seems to be a cumulative effect of
adverse events (Rutter and Maughan 1997), although
some authors argue that the abuse and neglect may not
be causally linked to the psychopathology, rather that
both may be due to a common genetic background of
both parent and offspring, for example, in terms of
shared impulsivity (Paris 1998). Some findings also sug-
gest that personality traits themselves might influence
the exposure to or occurrence of life events in adult life
(Poulton and Andrews 1992; Kendler et al. 2003).
Regardless of the causality, the findings indicate that
a history of childhood sexual abuse in a person with a
recent parasuicide may also be related to other forms of
severely dysfunctional relationships during childhood,
which need to be addressed in subsequent treatment
(Molnar et al. 2001). A person fulfilling the diagnostic
criteria of borderline personality disorder should, there-
fore, be carefully evaluated for different forms of se-
verely adverse family, social and interpersonal experi-
ences underlying the presenting symptoms.
Discussion
This follow-up study found an overall suicide rate ap-
proximately equivalent to that reported in other studies
(Paris 2002). The study supports earlier research linking
borderline personality disorder to recurrent suicidal be-
haviour and a prolonged need for psychiatric support
(e. g. Bongar et al. 1990; Jenkins et al. 2002; Suokas et al.
2001; Ostamo and Lonnqvist 2001; Tejedor et al. 1999).
However, in our study, the crude rates showed female
gender to be as strong a predictor of recurrent parasui-
cidal thoughts and acts as borderline personality disor-
der. This implies that simply being a woman is a risk fac-
tor for parasuicide, a finding that has also been reported
by Salander Renberg (2001).
A large number of the women diagnosed with bor-
derline personality disorder had a history of childhood
sexual abuse, a variable that is usually not taken into
consideration in studies of borderline personality disor-
der and suicidal behaviour. When accounting for a his-
tory of childhood sexual abuse, this rather than female
919
■
Methodological considerations
The initial interview included 81 % of the consecutive
parasuicide patients admitted for inpatient care at the
university hospital, which is the only hospital in the re-
gion. Of these, 80 % were included in the follow-up study
7 years later. In comparison with other studies, this is a
high response rate (Coll et al. 1998). Therefore, in spite of
the relatively small numbers, the figures should be rep-
resentative.
The results regarding sexual abuse are based on a
self-report questionnaire. Retrospective reports on sex-
ual abuse have been criticized on the basis that there
might be a recall problem (Paris 1995). It is well known
that direct questions on sexual abuse give much higher
rates than spontaneous reporting (Briere and Zaidi
1989). The confidential questionnaire used in the cur-
rent study is thought to give more reliable answers than
a personal interview, since it minimizes reporting bias
(Coll et al. 1998). In spite of this, our figures on sexual
abuse probably underestimate the real prevalence, since
there is significant underreporting even on direct ques-
tioning, as has been shown by Fergusson and Lynskey
(1995). Their findings were that there was a 50 % false
negative rate of reporting among those whose abuse had
been documented in a longitudinal birth cohort study.
Among those who had not been abused there were no
false positive reports (Fergusson et al. 2000).
Conclusion
The findings support the growing body of evidence link-
ing the characteristic symptoms of borderline personal-
ity disorder to childhood sexual abuse and other forms
of childhood abuse and neglect. They identify sexual
abuse rather than a diagnosis of borderline personality
disorder as the predictor for a poor longitudinal out-
come among parasuicide patients. The findings have a
bearing on our understanding and treatment of para-
suicide patients, especially those who fulfil the present
criteria for borderline personality disorder.
■
Acknowledgements
This study was funded by the Söderström-
Königska sjukhemmet Foundation (Swedish Medical Association)
and the Joint Committee of the Northern Health Region, Sweden.
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Childhood sexual abuse predicts poor outcome seven years after parasuicide, ♥ psychologia - inne (książki, ...

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